Ham and Cheese Breakfast Casserole with Biscuits

Easy, Cheesy Make-Ahead Brunch Favorite

Prep Time: 5 minutes
Cook Time: 45 minutes
Total Time: 50 minutes
Yield: 8 servings
Calories: 281 per serving

This hearty breakfast casserole is the perfect solution for feeding a hungry crowd during the holidays or any weekend brunch. With fluffy biscuits, savory ham, gooey cheese, and creamy eggs all baked in one dish, it’s simple, satisfying, and customizable. Top with gravy, hollandaise, or butter for the ultimate breakfast indulgence.

Ingredients

  • 8 large eggs
  • ½ cup milk
  • 1 tablespoon stone-ground mustard
  • Pinch of salt and pepper
  • 2 cans Grands biscuits, cut into quarters
  • ¼ lb deli ham or leftover holiday ham, chopped
  • 8 oz shredded triple cheddar blend, divided
  • Sliced green onions, for garnish

Instructions

  1. Preheat Oven
    Preheat your oven to 350ºF (175ºC). Grease a 9×13-inch casserole dish and set aside.
  2. Prepare Egg Mixture
    In a large bowl, whisk together the eggs, milk, mustard, salt, and pepper.
  3. Combine Ingredients
    Add the biscuit pieces, chopped ham, 4 oz of the shredded cheese, and the egg mixture to the bowl. Gently toss to evenly coat.
  4. Assemble Casserole
    Transfer everything into the prepared baking dish. Cover with foil.
  5. Bake
    Bake covered for 30 minutes. Remove foil, sprinkle with the remaining cheese, and bake uncovered for 15 additional minutes, or until golden and cooked through.
  6. Rest and Serve
    Let the casserole sit for 5–10 minutes before slicing. Garnish with sliced green onions and serve warm.

Serving Suggestions

  • Top with white breakfast gravy, hollandaise sauce, or a drizzle of melted butter for an extra-luxurious finish.
  • Serve with a side of fresh fruit or roasted potatoes for a complete brunch.

Notes

  • Make-Ahead Option: Assemble the casserole the night before, cover tightly, and refrigerate. In the morning, let it sit at room temperature for 15–20 minutes before baking as directed.
  • Cheese Choices: Feel free to substitute the triple cheddar blend with mozzarella, Monterey Jack, Swiss, or any combination of your favorites.
  • Ham Substitutes: Swap ham for cooked breakfast sausage, crumbled bacon, or a vegetarian sausage alternative for variety.
  • Add Veggies: For a boost of color and nutrition, try mixing in diced bell peppers, spinach, or sautéed onions.
  • Biscuit Tips: Be sure to cut biscuits into even, bite-sized pieces for uniform baking. Avoid overmixing to keep the biscuits fluffy.
  • Serving Sauce: This casserole pairs beautifully with white country gravy, hollandaise sauce, or a light drizzle of maple syrup for a sweet-savory twist.

Nutrition (Per Serving)

  • Calories: 281
  • Fat: 18g
  • Saturated Fat: 8g
  • Trans Fat: 1g
  • Cholesterol: 232mg
  • Sodium: 768mg
  • Carbohydrates: 10g
  • Sugar: 2g
  • Protein: 21g
Print
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Ham and Cheese Breakfast Casserole with Biscuits

  • Author: baking
  • Prep Time: 5 minutes
  • Cook Time: 45 minutes
  • Total Time: 50 minutes
  • Yield: 8 servings 1x

Description

This hearty breakfast casserole is the perfect solution for feeding a hungry crowd during the holidays or any weekend brunch. With fluffy biscuits, savory ham, gooey cheese, and creamy eggs all baked in one dish, it’s simple, satisfying, and customizable. Top with gravy, hollandaise, or butter for the ultimate breakfast indulgence.


Ingredients

Scale
  • 8 large eggs

  • ½ cup milk

  • 1 tablespoon stone-ground mustard

  • Pinch of salt and pepper

  • 2 cans Grands biscuits, cut into quarters

  • ¼ lb deli ham or leftover holiday ham, chopped

  • 8 oz shredded triple cheddar blend, divided

  • Sliced green onions, for garnish


Instructions

  • Preheat Oven
    Preheat your oven to 350ºF (175ºC). Grease a 9×13-inch casserole dish and set aside.

  • Prepare Egg Mixture
    In a large bowl, whisk together the eggs, milk, mustard, salt, and pepper.

  • Combine Ingredients
    Add the biscuit pieces, chopped ham, 4 oz of the shredded cheese, and the egg mixture to the bowl. Gently toss to evenly coat.

  • Assemble Casserole
    Transfer everything into the prepared baking dish. Cover with foil.

  • Bake
    Bake covered for 30 minutes. Remove foil, sprinkle with the remaining cheese, and bake uncovered for 15 additional minutes, or until golden and cooked through.

 

  • Rest and Serve
    Let the casserole sit for 5–10 minutes before slicing. Garnish with sliced green onions and serve warm.


Notes

  • Make-Ahead Option: Assemble the casserole the night before, cover tightly, and refrigerate. In the morning, let it sit at room temperature for 15–20 minutes before baking as directed.

  • Cheese Choices: Feel free to substitute the triple cheddar blend with mozzarella, Monterey Jack, Swiss, or any combination of your favorites.

  • Ham Substitutes: Swap ham for cooked breakfast sausage, crumbled bacon, or a vegetarian sausage alternative for variety.

  • Add Veggies: For a boost of color and nutrition, try mixing in diced bell peppers, spinach, or sautéed onions.

  • Biscuit Tips: Be sure to cut biscuits into even, bite-sized pieces for uniform baking. Avoid overmixing to keep the biscuits fluffy.

 

  • Serving Sauce: This casserole pairs beautifully with white country gravy, hollandaise sauce, or a light drizzle of maple syrup for a sweet-savory twist.

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